What is the treatment for sporotrichosis?

What is the treatment for sporotrichosis?

• A. Fluconazole
• B. Terbinafine
• C. Itraconazole
• D. Amphotericin B

Answer: (C)

Sporotrichosis is best treated with itraconazole because Sporothrix schenckii is usually highly susceptible to this azole, and itraconazole provides reliable, long-term oral therapy with good tissue penetration for the common cutaneous and lymphocutaneous forms. The typical approach is 200 mg once or twice daily for several months (often 3–6 months, guided by clinical resolution and duration after healing). Amphotericin B is reserved for more severe cases, such as disseminated disease or meningitis, due to its greater toxicity. Fluconazole and terbinafine can be used in some situations, but itraconazole remains the preferred first choice because of its demonstrated efficacy and favorable balance of safety and convenience.

Sporotrichosis is best treated with itraconazole because Sporothrix schenckii is usually highly susceptible to this azole, and itraconazole provides reliable, long-term oral therapy with good tissue penetration for the common cutaneous and lymphocutaneous forms. The typical approach is 200 mg once or twice daily for several months (often 3–6 months, guided by clinical resolution and duration after healing).

Amphotericin B is reserved for more severe cases, such as disseminated disease or meningitis, due to its greater toxicity. Fluconazole and terbinafine can be used in some situations, but itraconazole remains the preferred first choice because of its demonstrated efficacy and favorable balance of safety and convenience.