In chronic renal failure, which antihypertensive is listed as part of the recommended therapy?

In chronic renal failure, which antihypertensive is listed as part of the recommended therapy?

• A. ACE inhibitors
• B. Diuretics
• C. Nitrates
• D. Beta blockers

Answer: (B)

In chronic kidney disease, controlling blood pressure often hinges on removing excess fluid and salt from the body. Diuretics do this by increasing urine output, which lowers extracellular fluid volume and helps reduce blood pressure. Loop diuretics are particularly useful when kidney function is reduced because they remain effective even with low GFR, while thiazides lose effectiveness as GFR falls. This makes diuretics a common staple in CKD-related hypertension management, especially for addressing edema and volume overload. Be mindful of potential electrolyte disturbances (such as low potassium or sodium) and dehydration, and monitor kidney function and fluid status. While other antihypertensives like ACE inhibitors can offer kidney-protective benefits, the option most routinely listed for CKD-related hypertension due to its volume-reducing effects is diuretics.

In chronic kidney disease, controlling blood pressure often hinges on removing excess fluid and salt from the body. Diuretics do this by increasing urine output, which lowers extracellular fluid volume and helps reduce blood pressure. Loop diuretics are particularly useful when kidney function is reduced because they remain effective even with low GFR, while thiazides lose effectiveness as GFR falls. This makes diuretics a common staple in CKD-related hypertension management, especially for addressing edema and volume overload.

Be mindful of potential electrolyte disturbances (such as low potassium or sodium) and dehydration, and monitor kidney function and fluid status. While other antihypertensives like ACE inhibitors can offer kidney-protective benefits, the option most routinely listed for CKD-related hypertension due to its volume-reducing effects is diuretics.