For otitis externa, which topical regimen is commonly used?

For otitis externa, which topical regimen is commonly used?

• A. Ciprofloxacin ear drops
• B. Polymyxin B, Neomycin, and Hydrocortisone
• C. Amoxicillin
• D. Erythromycin ointment

Answer: (B)

Otitis externa is treated with topical therapy because the infection is confined to the ear canal. A combination of antibiotics with a steroid is commonly used because it provides broad antimicrobial coverage and helps reduce inflammation and edema, which improves drainage and comfort. The pairing of polymyxin B and neomycin offers broad activity against common outer-ear pathogens, including Gram-negative and Gram-positive bacteria, while hydrocortisone decreases itch and swelling that can obstruct the canal and hinder treatment. This single-regimen approach is convenient and effective for many cases. Be mindful that if the tympanic membrane is perforated or there’s a risk of it being perforated, aminoglycoside-containing drops (like neomycin) can be ototoxic, so alternatives such as fluoroquinolone-only drops may be preferred in those situations. While other regimens like ciprofloxacin ear drops are also used in certain scenarios, the commonly used topical combination with a steroid is the best-supported default choice for uncomplicated otitis externa.

Otitis externa is treated with topical therapy because the infection is confined to the ear canal. A combination of antibiotics with a steroid is commonly used because it provides broad antimicrobial coverage and helps reduce inflammation and edema, which improves drainage and comfort. The pairing of polymyxin B and neomycin offers broad activity against common outer-ear pathogens, including Gram-negative and Gram-positive bacteria, while hydrocortisone decreases itch and swelling that can obstruct the canal and hinder treatment. This single-regimen approach is convenient and effective for many cases.

Be mindful that if the tympanic membrane is perforated or there’s a risk of it being perforated, aminoglycoside-containing drops (like neomycin) can be ototoxic, so alternatives such as fluoroquinolone-only drops may be preferred in those situations. While other regimens like ciprofloxacin ear drops are also used in certain scenarios, the commonly used topical combination with a steroid is the best-supported default choice for uncomplicated otitis externa.